Paracchini et al have published a study that looked for a correlation between prostate cancer and Y haplogroups. The paper includes the Y haplogroups for 1028 men from California and Hawaii. The results are separated into four different ethnic groups: Caucasian, Hispanic, African-American, and Japanese. In each ethnic category they tested 100+ men with prostate cancer and 100+ randomly chosen men who acted as the controls. They looked for haplogroups that showed higher percentages among the men with prostate cancer than was seen among the randomly chosen men. The only haplogroup that was found to show a statistically significant correlation with prostate cancer was YCC haplogroup O3.
The table below shows the percentages among the four ethnic groups that belonged to each haplogroup. The paper gives separate results for the prostate cancer cases and the controls, but except for O3, I have combined them into total percentages for each ethnic group. For the O3 haplogroups the percentages given are just those for the control group.
| African- | |||||
| YCC (2002) | Caucasian | Hispanic | American | Japanese | |
| Haplogroup | (202 men) | (284 men) | (247 men) | (295 men) | |
| B* | 0.0 | 0.0 | 0.7 | 0.0 | |
| B1 | 0.0 | 0.0 | 0.4 | 0.0 | |
| B2a1 | 0.0 | 0.0 | 1.4 | 0.0 | |
| C* | 0.0 | 0.3 | 0.0 | 6.1 | |
| C1 | 0.0 | 0.0 | 0.0 | 4.9 | |
| D1 | 0.0 | 0.0 | 0.0 | 0.4 | |
| D2b1 | 0.0 | 0.3 | 0.0 | 17.4 | |
| D2a | 0.0 | 0.0 | 0.0 | 13.8 | |
| E* | 0.0 | 0.0 | 0.4 | 0.0 | |
| E1* | 0.0 | 0.0 | 2.8 | 0.0 | |
| E2b | 0.0 | 0.0 | 3.2 | 0.0 | |
| E3a* | 0.0 | 1.0 | 49.6 | 0.0 | Common in Sub-Saharan Africa |
| E3a1 | 0.0 | 0.0 | 1.4 | 0.0 | |
| E3b* | 0.5 | 1.0 | 0.4 | 0.0 | |
| E3b1* | 2.8 | 3.7 | 1.1 | 0.0 | |
| E3b2* | 0.0 | 2.4 | 0.0 | 0.0 | Common in Spain and NW Africa |
| E3b3* | 0.5 | 0.0 | 0.0 | 0.0 | |
| E3b3a* | 1.9 | 1.7 | 0.4 | 0.0 | |
| G (or F*) | 6.2 | 8.1 | 1.4 | 0.4 | Formal name: FxHIJK |
| I | 19.0 | 4.4 | 4.9 | 0.0 | I1a2, I1a3, and I1b2a were not seen |
| I1b2* | 0.0 | 2.0 | 0.0 | 0.0 | Markers for I1a, I1a1 and I1b were not tested |
| J2* | 2.4 | 3.4 | 1.1 | 0.0 | |
| J2e1* | 0.9 | 1.0 | 0.7 | 0.0 | |
| J2f* | 0.9 | 1.0 | 0.0 | 0.0 | |
| J2f1 | 0.9 | 0.3 | 1.1 | 0.0 | |
| K* (or K1) | 0.0 | 0.0 | 0.0 | 0.4 | Formal name: Kx(K2,K3) |
| K2 | 1.4 | 2.0 | 0.0 | 0.0 | |
| N3 | 0.9 | 0.0 | 0.0 | 1.2 | |
| O* | 0.9 | 0.7 | 0.0 | 28.7 | |
| O1* | 0.0 | 0.0 | 0.0 | 2.8 | |
| O3e1* | 0.0 | 0.3 | 0.0 | 5.8 | |
| O3e* | 0.0 | 0.3 | 0.0 | 4.1 | |
| O3* | 0.0 | 0.0 | 0.0 | 8.3 | |
| O3d* | 0.0 | 0.3 | 0.0 | 0.8 | |
| Q3 | 1.4 | 12.2 | 0.7 | 0.0 | Over 50% of Native American men are Q3. |
| R* | 0.5 | 3.4 | 0.4 | 0.0 | Formal name: Px(Q,R1,R2) |
| R1a1 | 10.0 | 1.7 | 2.8 | 0.0 | |
| R1* | 48.8 | 46.1 | 25.4 | 0.8 | Probably R1b - but they didn't test P25 marker. |
| R1b6 | 0.0 | 1.7 | 0.0 | 0.0 | One of the Basque R1b subgroups. |
| R1b8 | 0.0 | 0.3 | 0.0 | 0.0 | One of the Basque R1b subgroups. |
